The Emperor of All Maladies book cover

The Emperor of All Maladies by Siddhartha Mukherjee Summary

The Emperor of All Maladies
Siddhartha Mukherjee
4.34 (111725 Reviews)
Science
Health
Biography
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Overview of The Emperor of All Maladies

Pulitzer Prize-winning "Emperor of All Maladies" charts cancer's 4,000-year journey through human history. Recommended by Bill Gates and transformed into a PBS documentary, Mukherjee's "biography of cancer" reveals why this cellular rebel remains our most formidable medical adversary.

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Part 1: The Ancient Enemy

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Cancer, the emperor of all maladies, the king of terrors, has been a relentless adversary to humanity for millennia. My journey into the heart of this disease began during my fellowship at Massachusetts General Hospital, where I encountered a 31-year-old mother named Carla Reed, who had just been diagnosed with leukemia. Her story, like many others, is a testament to the enduring and often brutal battle against cancer. The history of cancer stretches back 4,600 years to ancient Egypt, where the physician Imhotep first identified the disease. In those times, cancer was a mysterious and often fatal affliction. The Greeks, with their limited understanding of cells, attributed illness to an imbalance of the four cardinal fluids: blood, black bile, yellow bile, and phlegm. Galen, a prominent Greek physician, believed cancer was caused by an excess of black bile, a theory that persisted until the 16th century. One of the earliest recorded surgical interventions for cancer was the excision of a breast tumor from Atossa, the queen of Persia, by a Greek slave named Democedes in 440 BC. This procedure, though temporary in its success, marked one of the first attempts to combat the disease surgically.

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Part 2: The Evolution of Treatment

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Part 3: The War on Cancer

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Part 4: The Genetic Frontier

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Part 5: The Human Element

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Part 6: The Ongoing War

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"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."

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"Reading used to feel like a chore. Now it’s just part of my lifestyle."

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"Feels effortless compared to reading. I’ve finished 6 books this month already."

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"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

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@Raaaaaachelw
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"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."

@Matt, YC alum
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comments
12
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"Reading used to feel like a chore. Now it’s just part of my lifestyle."

@Erin, Investment Banking Associate , NYC
platform
comments
254
likes
17

"Feels effortless compared to reading. I’ve finished 6 books this month already."

@djmikemoore
platform
star
star
star
star
star

"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

@Pitiful
platform
comments
96
likes
4.5K

"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."

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"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"

@Jaded_Falcon
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"It is great for me to learn something from the book without reading it."

@OojasSalunke
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"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."

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37
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