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    Copertina del libro Микрофлюидика: как химия в каналах меняет синтез полимеров
    ПРОЦЕССЫ И АППАРАТЫ ХИМИЧЕСКИХ ТЕХНОЛОГИЙ/PROCESSES AND DEVICES OF CHEMICAL TECHNOLOGIES DOI: https://doi.org/10.60797/IRJ.2024.144.41 EDN: KJXTWS ОСНОВНЫЕ ПРИНЦИПЫ ПРОЕКТИРОВАНИЯ, ИЗГОТОВЛЕНИЯ И ПРИМЕНЕНИЯ МИКРОРЕАКТОРОВ Обзор Шишанов М.В. 1, Кук Х.Г. 2, *, Досов К.А. 3, Большаков И.А. 4, Яшунин Д.В. 5, Морозов Н.В. 1 ORCID : 0000-0003-2861-5878; 2 ORCID : 0009-0005-7115-6760; 3 ORCID : 0009-0000-7243-691X; 4 ORCID : 0009-0002-3600-2123; 5 ORCID : 0009-0002-5741-3626; 6 ORCID : 0009-0001-4045-5355; 1, 2, 3, 5, 6 Российский химико-технологический университет им. Д.И. Менделеева, Москва, Российская Федерация 4 Российский химико-технологический университет им. Д.И. Менделеева, Москва, Российская Федерация * Корреспондирующий автор (kuk.khristofor[at]inbox.ru) Аннотация В данной обзорно-аналитической статье рассматриваются разработка, изготовление и применение малотоннажных микрореакторных систем. Технология микрореакций и микрореакторные системы направлены на повышение интенсификации и безопасности химических процессов. Технология микрореакций совершенствуется постоянно, в связи с чем обзор современных методов проектирования, изготовления, применения является важным аспектом для современного понимания развития малотоннажной химии. Микрофлюидные реактора получили широкое распространение в различных областях науки: медицина, специальная химия, биохимия, ядерная химия и многие другие. Они пользуются успехом ввиду обеспечения повышенного массо- и теплообмена, лучшей интенсификации процесса и, как следствие, высокого выхода продукта. Обсуждаются материалы, типы реакций, технологии изготовления, области применения. Ключевые слова: микрореактор, микрореакторные системы, микросмешение, изготовление. BASIC PRINCIPLES OF DESIGN, MANUFACTURE AND APPLICATION OF MICROREACTORS Review article Shishanov M.V. 1, Cook C.G. 2, *, Dosov K.A. 3, Bolshakov I.A. 4, Yashunin D.V. 5, Morozov N.V. 1 ORCID : 0000-0003-2861-5878; 2 ORCID : 0009-0005-7115-6760; 3 ORCID : 0009-0000-7243-691X; 4 ORCID : 0009-0002-3600-2123; 5 ORCID : 0009-0002-5741-3626; 6 ORCID : 0009-0001-4045-5355; 1, 2, 3, 5, 6 D.I. Mendeleev Russian University of Chemical Technology, Moscow, Russian Federation 4 D. I. Mendeleev Russian University Of Chemical Technology, Moscow, Russian Federation * Corresponding author (kuk.khristofor[at]inbox.ru) Abstract This review and analysis article examines the design, fabrication and application of low-tonnage microreactor systems. Microreaction technology and microreactor systems are aimed at increasing the intensification and safety of chemical processes. Microreaction technology is improving continuously, therefore, a review of current methods of design, fabrication, and application is an important aspect for the current understanding of the development of low-tonnage chemistry. Microfluidic reactors are widely spread in various fields of science: medicine, special chemistry, biochemistry, nuclear chemistry and many others. They are favoured due to the provision of increased mass and heat transfer, better process intensification and, as a consequence, high product yields. Materials, reaction types, fabrication techniques, and applications are discussed. Keywords: microreactor, microreactor systems, micromixing, manufacturing. Введение Первые микрореакторы были изготовлены в начале 1990-х годов Центральным экспериментальным отделом Исследовательского центра Карлсруэ (Германия). Микрореакторы были побочным продуктом производства разделительных сопел для обогащения урана [1]. Центр занимался разработкой высокоэффективных микроструктурированных теплообменников. В связи с изменением политики Германии в области исследований ядерных технологий в 90-х годах, резкое сокращение финансирования заставило исследователей искать новое применение данной технологии. Группа исследователей изучила возможность применения микроструктурированных теплообменников для проведения высокоэкзотермических и опасных химических реакций. Новая концепция получила название «технология микрореакций» или «микротехнология». Далее в работах [2], [3], [4] было показано, что микрореакторы с глубиной канала 100-1000 микрометров могут быть использованы для проведения сложных реакций, 1Химический синтез с помощью микрофлюидики - azimp-micro.ruPrecision Polymer Design in Microstructured Flow Reactors: Improved Control and First Upscale at OnceИзготовление микрофлюидных чипов из ...
    7 sources
    Микрофлюидика: как химия в каналах меняет синтез полимеров

    Традиционные реакторы не справляются с перегревом, но микрофлюидика решает проблему. Узнайте, как потоковый синтез создает идеальные молекулы.

    Copertina del libro Микрофлюидика: как химия в каналах меняет синтез полимеров
    ПРОЦЕССЫ И АППАРАТЫ ХИМИЧЕСКИХ ТЕХНОЛОГИЙ/PROCESSES AND DEVICES OF CHEMICAL TECHNOLOGIES DOI: https://doi.org/10.60797/IRJ.2024.144.41 EDN: KJXTWS ОСНОВНЫЕ ПРИНЦИПЫ ПРОЕКТИРОВАНИЯ, ИЗГОТОВЛЕНИЯ И ПРИМЕНЕНИЯ МИКРОРЕАКТОРОВ Обзор Шишанов М.В. 1, Кук Х.Г. 2, *, Досов К.А. 3, Большаков И.А. 4, Яшунин Д.В. 5, Морозов Н.В. 1 ORCID : 0000-0003-2861-5878; 2 ORCID : 0009-0005-7115-6760; 3 ORCID : 0009-0000-7243-691X; 4 ORCID : 0009-0002-3600-2123; 5 ORCID : 0009-0002-5741-3626; 6 ORCID : 0009-0001-4045-5355; 1, 2, 3, 5, 6 Российский химико-технологический университет им. Д.И. Менделеева, Москва, Российская Федерация 4 Российский химико-технологический университет им. Д.И. Менделеева, Москва, Российская Федерация * Корреспондирующий автор (kuk.khristofor[at]inbox.ru) Аннотация В данной обзорно-аналитической статье рассматриваются разработка, изготовление и применение малотоннажных микрореакторных систем. Технология микрореакций и микрореакторные системы направлены на повышение интенсификации и безопасности химических процессов. Технология микрореакций совершенствуется постоянно, в связи с чем обзор современных методов проектирования, изготовления, применения является важным аспектом для современного понимания развития малотоннажной химии. Микрофлюидные реактора получили широкое распространение в различных областях науки: медицина, специальная химия, биохимия, ядерная химия и многие другие. Они пользуются успехом ввиду обеспечения повышенного массо- и теплообмена, лучшей интенсификации процесса и, как следствие, высокого выхода продукта. Обсуждаются материалы, типы реакций, технологии изготовления, области применения. Ключевые слова: микрореактор, микрореакторные системы, микросмешение, изготовление. BASIC PRINCIPLES OF DESIGN, MANUFACTURE AND APPLICATION OF MICROREACTORS Review article Shishanov M.V. 1, Cook C.G. 2, *, Dosov K.A. 3, Bolshakov I.A. 4, Yashunin D.V. 5, Morozov N.V. 1 ORCID : 0000-0003-2861-5878; 2 ORCID : 0009-0005-7115-6760; 3 ORCID : 0009-0000-7243-691X; 4 ORCID : 0009-0002-3600-2123; 5 ORCID : 0009-0002-5741-3626; 6 ORCID : 0009-0001-4045-5355; 1, 2, 3, 5, 6 D.I. Mendeleev Russian University of Chemical Technology, Moscow, Russian Federation 4 D. I. Mendeleev Russian University Of Chemical Technology, Moscow, Russian Federation * Corresponding author (kuk.khristofor[at]inbox.ru) Abstract This review and analysis article examines the design, fabrication and application of low-tonnage microreactor systems. Microreaction technology and microreactor systems are aimed at increasing the intensification and safety of chemical processes. Microreaction technology is improving continuously, therefore, a review of current methods of design, fabrication, and application is an important aspect for the current understanding of the development of low-tonnage chemistry. Microfluidic reactors are widely spread in various fields of science: medicine, special chemistry, biochemistry, nuclear chemistry and many others. They are favoured due to the provision of increased mass and heat transfer, better process intensification and, as a consequence, high product yields. Materials, reaction types, fabrication techniques, and applications are discussed. Keywords: microreactor, microreactor systems, micromixing, manufacturing. Введение Первые микрореакторы были изготовлены в начале 1990-х годов Центральным экспериментальным отделом Исследовательского центра Карлсруэ (Германия). Микрореакторы были побочным продуктом производства разделительных сопел для обогащения урана [1]. Центр занимался разработкой высокоэффективных микроструктурированных теплообменников. В связи с изменением политики Германии в области исследований ядерных технологий в 90-х годах, резкое сокращение финансирования заставило исследователей искать новое применение данной технологии. Группа исследователей изучила возможность применения микроструктурированных теплообменников для проведения высокоэкзотермических и опасных химических реакций. Новая концепция получила название «технология микрореакций» или «микротехнология». Далее в работах [2], [3], [4] было показано, что микрореакторы с глубиной канала 100-1000 микрометров могут быть использованы для проведения сложных реакций, 1Химический синтез с помощью микрофлюидики - azimp-micro.ruPrecision Polymer Design in Microstructured Flow Reactors: Improved Control and First Upscale at OnceИзготовление микрофлюидных чипов из ...
    7 sources
    Микрофлюидика: как химия в каналах меняет синтез полимеров
    Традиционные реакторы не справляются с перегревом, но микрофлюидика решает проблему. Узнайте, как потоковый синтез создает идеальные молекулы.
    Copertina del libro Automating STIG Compliance in DevSecOps
    STIG Compliance Automation in Kubernetes | RutagonAutomating STIG Compliance with Ansible and GitLab PipelinesSTIG in Action: 4 Lessons on Automating Compliance with MITRE SAF - Security BoulevardMITRE SAF CLI
    8 sources
    Automating STIG Compliance in DevSecOps

    Manual security hardening can't keep up with cloud-native speeds. Learn to bake STIG controls into your pipelines for automated, audit-ready security.

    Copertina del libro Automating STIG Compliance in DevSecOps
    STIG Compliance Automation in Kubernetes | RutagonAutomating STIG Compliance with Ansible and GitLab PipelinesSTIG in Action: 4 Lessons on Automating Compliance with MITRE SAF - Security BoulevardMITRE SAF CLI
    8 sources
    Automating STIG Compliance in DevSecOps
    Manual security hardening can't keep up with cloud-native speeds. Learn to bake STIG controls into your pipelines for automated, audit-ready security.
    Copertina del libro The Science of Chest Hair for Amy
    Terminal Hair: Function & ExamplesIn brief: What is the structure of hair and how does it grow? - InformedHealth.org - NCBI BookshelfShedding Our Body Hair May Have Had Evolutionary ...All About Puberty (for Kids) | Nemours KidsHealth
    4 sources
    The Science of Chest Hair for Amy

    Ever wonder why grown-ups have fuzzy chests while yours is smooth? Discover the secret of our invisible sweaters and how our bodies change as we grow.

    Copertina del libro The Science of Chest Hair for Amy
    Terminal Hair: Function & ExamplesIn brief: What is the structure of hair and how does it grow? - InformedHealth.org - NCBI BookshelfShedding Our Body Hair May Have Had Evolutionary ...All About Puberty (for Kids) | Nemours KidsHealth
    4 sources
    The Science of Chest Hair for Amy
    Ever wonder why grown-ups have fuzzy chests while yours is smooth? Discover the secret of our invisible sweaters and how our bodies change as we grow.
    Copertina del libro Boost Your VO2 Max, Extend Your Life
    The Oxygen AdvantageThe New Competitive Runner's HandbookMind GymEndure: Mind, Body, and the Curiously Elastic Limits of Human Performance
    16 sources
    Boost Your VO2 Max, Extend Your Life

    Discover why VO2 max is the gold standard for measuring aerobic fitness and longevity. Learn science-backed strategies to improve this crucial metric regardless of your current fitness level.

    Copertina del libro Boost Your VO2 Max, Extend Your Life
    The Oxygen AdvantageThe New Competitive Runner's HandbookMind GymEndure: Mind, Body, and the Curiously Elastic Limits of Human Performance
    16 sources
    Boost Your VO2 Max, Extend Your Life
    Discover why VO2 max is the gold standard for measuring aerobic fitness and longevity. Learn science-backed strategies to improve this crucial metric regardless of your current fitness level.
    Copertina del libro Getting enough sleep isn't always about eight hours
    The Sleep SolutionHello SleepInner Clock
    23 sources
    Getting enough sleep isn't always about eight hours

    Struggling to feel rested? We explore why sleep needs vary by age and how simple habits like stimulus control can help you finally wake up refreshed.

    Copertina del libro Getting enough sleep isn't always about eight hours
    The Sleep SolutionHello SleepInner Clock
    23 sources
    Getting enough sleep isn't always about eight hours
    Struggling to feel rested? We explore why sleep needs vary by age and how simple habits like stimulus control can help you finally wake up refreshed.
    Copertina del libro The Science of Swallowing Semen
    Table 1. [The Composition of Human Semen (adapted from Ganong )]. - Endotext - NCBI BookshelfSwallowing semen: Safety, benefits, and risks - Medical News TodaySwallowing Semen: What You Should Know | DTAP Clinic SingaporeIngesting Semen: Are There Nutrients, and Is It Safe? - WebMD
    6 sources
    The Science of Swallowing Semen

    Is it actually safe or nutritious? Explore the biological makeup of semen, the reality of STI risks, and the surprising ways it interacts with the body.

    Copertina del libro The Science of Swallowing Semen
    Table 1. [The Composition of Human Semen (adapted from Ganong )]. - Endotext - NCBI BookshelfSwallowing semen: Safety, benefits, and risks - Medical News TodaySwallowing Semen: What You Should Know | DTAP Clinic SingaporeIngesting Semen: Are There Nutrients, and Is It Safe? - WebMD
    6 sources
    The Science of Swallowing Semen
    Is it actually safe or nutritious? Explore the biological makeup of semen, the reality of STI risks, and the surprising ways it interacts with the body.
    Copertina del libro Kitten Sleep: The Biological Construction Zone
    Do Kittens Sleep a Lot? Vet-Reviewed Facts & FAQHow Much Sleep Is Normal For Kittens? | ChewyWhy Is My Kitten Sleeping So Much? - LemonadeWhy Kittens Sleep So Much: Growth Hormone Facts
    5 sources
    Kitten Sleep: The Biological Construction Zone

    Ever wonder why kittens sleep up to 22 hours a day? Discover the evolutionary science behind their deep rest and how it fuels their growth.

    Copertina del libro Kitten Sleep: The Biological Construction Zone
    Do Kittens Sleep a Lot? Vet-Reviewed Facts & FAQHow Much Sleep Is Normal For Kittens? | ChewyWhy Is My Kitten Sleeping So Much? - LemonadeWhy Kittens Sleep So Much: Growth Hormone Facts
    5 sources
    Kitten Sleep: The Biological Construction Zone
    Ever wonder why kittens sleep up to 22 hours a day? Discover the evolutionary science behind their deep rest and how it fuels their growth.
    Copertina del libro Rethinking Lipid Management for Family Medicine
    The Great Cholesterol ConThe Great Cholesterol MythCholesterol ClarityPrevent and Reverse Heart Disease
    12 sources
    Rethinking Lipid Management for Family Medicine

    Challenge traditional lipid screening assumptions and discover streamlined, evidence-based approaches that actually work in busy family practice settings.

    Copertina del libro Rethinking Lipid Management for Family Medicine
    The Great Cholesterol ConThe Great Cholesterol MythCholesterol ClarityPrevent and Reverse Heart Disease
    12 sources
    Rethinking Lipid Management for Family Medicine
    Challenge traditional lipid screening assumptions and discover streamlined, evidence-based approaches that actually work in busy family practice settings.
    Copertina del libro HALEU: Clean Energy or Weapons Risk?
    Command and ControlThe Doomsday MachineFukushimaThe Sum of All Fears
    13 sources
    HALEU: Clean Energy or Weapons Risk?

    Explore the debate around High-Assay Low-Enriched Uranium (HALEU), a promising fuel for next-gen nuclear reactors that some experts warn could potentially be weaponized, raising security concerns alongside its clean energy benefits.

    Copertina del libro HALEU: Clean Energy or Weapons Risk?
    Command and ControlThe Doomsday MachineFukushimaThe Sum of All Fears
    13 sources
    HALEU: Clean Energy or Weapons Risk?
    Explore the debate around High-Assay Low-Enriched Uranium (HALEU), a promising fuel for next-gen nuclear reactors that some experts warn could potentially be weaponized, raising security concerns alongside its clean energy benefits.
    Copertina del libro The Quantum Leap: Beyond Binary Boundaries
    Entanglement: The Greatest Mystery in PhysicsThe Emperor's New MindDancing Wu Li MastersQuantum Supremacy
    26 sources
    The Quantum Leap: Beyond Binary Boundaries

    Explore the 'spooky' world of qubits and superposition to understand how quantum computers solve impossible problems, from revolutionary medicine to the future of global encryption.

    Copertina del libro The Quantum Leap: Beyond Binary Boundaries
    Entanglement: The Greatest Mystery in PhysicsThe Emperor's New MindDancing Wu Li MastersQuantum Supremacy
    26 sources
    The Quantum Leap: Beyond Binary Boundaries
    Explore the 'spooky' world of qubits and superposition to understand how quantum computers solve impossible problems, from revolutionary medicine to the future of global encryption.
    Copertina del libro The Arrow of Time and Cosmic Awakening
    Arrow of timeTimeline of the early universeLife as a Guide to Its Own Origins | Annual ReviewsA General Theory of Abiogenesis: Thermodynamic Selection and the Emergence of Life
    7 sources
    The Arrow of Time and Cosmic Awakening

    How did a tiny singularity become a conscious reality? Explore the one-way flow from entropy to life and how the universe finally learned to see itself.

    Copertina del libro The Arrow of Time and Cosmic Awakening
    Arrow of timeTimeline of the early universeLife as a Guide to Its Own Origins | Annual ReviewsA General Theory of Abiogenesis: Thermodynamic Selection and the Emergence of Life
    7 sources
    The Arrow of Time and Cosmic Awakening
    How did a tiny singularity become a conscious reality? Explore the one-way flow from entropy to life and how the universe finally learned to see itself.
    Copertina del libro A Ciência Invisível no seu Banheiro
    UMECTANTES -É umectante! Ou será emoliente? » Cosmética em Foco<data:blog.pageTitle/>Conservantes Cosméticos: Como Validar Eficácia com Base Científica e Regulatória.
    9 sources
    A Ciência Invisível no seu Banheiro

    Da química dos hidratantes à revolução da penicilina, descubra como a biotecnologia protege sua pele e garante a segurança dos produtos que você usa.

    Copertina del libro A Ciência Invisível no seu Banheiro
    UMECTANTES -É umectante! Ou será emoliente? » Cosmética em Foco<data:blog.pageTitle/>Conservantes Cosméticos: Como Validar Eficácia com Base Científica e Regulatória.
    9 sources
    A Ciência Invisível no seu Banheiro
    Da química dos hidratantes à revolução da penicilina, descubra como a biotecnologia protege sua pele e garante a segurança dos produtos que você usa.
    Copertina del libro Adult Acne and the Breakout Cascade
    Dermatologist Debunks the Myth That Only Teenagers Get Acne...Here's What Actually Causes Breakouts - acneadvocate.comAdult Acne: Causes and TreatmentsHormonal Acne vs Bacterial Acne - Tareen DermatologyHormonal Acne vs Bacterial Acne: Key Differences
    5 sources
    Adult Acne and the Breakout Cascade

    Struggling with breakouts long after your teens? Learn why hormones and biology trigger adult acne and how to update your routine for clearer skin.

    Copertina del libro Adult Acne and the Breakout Cascade
    Dermatologist Debunks the Myth That Only Teenagers Get Acne...Here's What Actually Causes Breakouts - acneadvocate.comAdult Acne: Causes and TreatmentsHormonal Acne vs Bacterial Acne - Tareen DermatologyHormonal Acne vs Bacterial Acne: Key Differences
    5 sources
    Adult Acne and the Breakout Cascade
    Struggling with breakouts long after your teens? Learn why hormones and biology trigger adult acne and how to update your routine for clearer skin.
    Copertina del libro Biological aging is faster than you think
    OutliveThe Telomere EffectSuper HumanThe Biology of Aging
    23 sources
    Biological aging is faster than you think

    Is your internal clock moving faster than your birthday? Discover why aging happens in bursts and how new cellular science helps you slow the process.

    Copertina del libro Biological aging is faster than you think
    OutliveThe Telomere EffectSuper HumanThe Biology of Aging
    23 sources
    Biological aging is faster than you think
    Is your internal clock moving faster than your birthday? Discover why aging happens in bursts and how new cellular science helps you slow the process.
    Copertina del libro F-15 Eagle: The 104-0 Legend
    F-15 Eagle HistoryF-15 Eagle > Air Force > Fact Sheet DisplayMcDonnell Douglas F-15A Streak EagleCheckpoints: The F-15 Eagle's 50 years of air dominance
    8 sources
    F-15 Eagle: The 104-0 Legend

    After struggling in the skies over Vietnam, the U.S. built the F-15 to reclaim air supremacy. Explore the engineering behind its perfect combat record.

    Copertina del libro F-15 Eagle: The 104-0 Legend
    F-15 Eagle HistoryF-15 Eagle > Air Force > Fact Sheet DisplayMcDonnell Douglas F-15A Streak EagleCheckpoints: The F-15 Eagle's 50 years of air dominance
    8 sources
    F-15 Eagle: The 104-0 Legend
    After struggling in the skies over Vietnam, the U.S. built the F-15 to reclaim air supremacy. Explore the engineering behind its perfect combat record.
    Copertina del libro The Mechanics of the Amplifier
    What Is An Amplifier? Types, Working, And Applications | RA ElectronicsTypes of Amplifiers : Circuits, Working & Their ApplicationsHow Amplifiers Work | HowStuffWorksUnderstanding Amplifiers – NOVO Audio and Technology Magazine
    7 sources
    The Mechanics of the Amplifier

    How do we turn a tiny electrical ripple into a tidal wave of sound? Explore the science of gain and the hidden hardware that powers our modern world.

    Copertina del libro The Mechanics of the Amplifier
    What Is An Amplifier? Types, Working, And Applications | RA ElectronicsTypes of Amplifiers : Circuits, Working & Their ApplicationsHow Amplifiers Work | HowStuffWorksUnderstanding Amplifiers – NOVO Audio and Technology Magazine
    7 sources
    The Mechanics of the Amplifier
    How do we turn a tiny electrical ripple into a tidal wave of sound? Explore the science of gain and the hidden hardware that powers our modern world.
    Copertina del libro 大模型榜单背后的统计陷阱
    Direct source: arxiv.org
    1 source
    大模型榜单背后的统计陷阱

    Lena 和 Miles 揭秘大模型评估中被忽视的统计误差,指出榜单微弱分差可能只是随机噪音。通过引入置信区间和配对实验等科学方法,教你如何穿透排名乱象,看清模型真正的技术实力。

    Copertina del libro 大模型榜单背后的统计陷阱
    Direct source: arxiv.org
    1 source
    大模型榜单背后的统计陷阱
    Lena 和 Miles 揭秘大模型评估中被忽视的统计误差,指出榜单微弱分差可能只是随机噪音。通过引入置信区间和配对实验等科学方法,教你如何穿透排名乱象,看清模型真正的技术实力。
    Copertina del libro The Invisible Architecture: Neuroscience of Sonic Branding
    The Brain SellSonic BoomBuyologyBrainfluence
    17 sources
    The Invisible Architecture: Neuroscience of Sonic Branding

    Explore how strategic sound bypasses visual logic to trigger instant emotional recall and long-term brand loyalty through the science of psychoacoustics.

    Copertina del libro The Invisible Architecture: Neuroscience of Sonic Branding
    The Brain SellSonic BoomBuyologyBrainfluence
    17 sources
    The Invisible Architecture: Neuroscience of Sonic Branding
    Explore how strategic sound bypasses visual logic to trigger instant emotional recall and long-term brand loyalty through the science of psychoacoustics.
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