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December 2013. A two-year-old boy named Emile plays near a hollow tree in Meliandou, Guinea, while his mother washes clothes nearby. Inside the tree, small bats-what locals call "flying mice"-hang in the darkness. Children sometimes hunt these bats, smoking them out and roasting them over fires. Emile is too young to hunt, but perhaps he touches one. Perhaps he tastes something. Perhaps bat blood or urine finds its way onto his skin. Whatever the exact moment, it changes everything. By Christmas Eve, Emile develops black diarrhea. Four days later, he's dead. Within weeks, his sister, mother, and grandmother follow. The virus-Zaire ebolavirus, capable of liquefying human organs-has emerged from what scientists call the "virosphere," that vast ocean of constantly evolving pathogens. It had appeared once before in 1976, killed hundreds in central Africa, then vanished back into the forest. Now it's back, 2,000 miles away, in a region where Guinea, Sierra Leone, and Liberia converge. Here, the Kissi people move freely across borders, and recent deforestation has created new contact zones between wilderness and human settlements. A microscopic strand of RNA, just 80 nanometers wide, has found its way from forest to child-and is now spreading with terrifying speed.