What is *Why Zebras Don't Get Ulcers* about?

*Why Zebras Don't Get Ulcers* explores how chronic stress harms human health, contrasting short-term stress responses in animals (like zebras fleeing predators) with modern humans’ prolonged psychological stressors. Robert Sapolsky explains how cortisol and other stress hormones contribute to ulcers, heart disease, and depression, while offering science-backed coping strategies. The book blends biology, neuroscience, and practical advice for stress management.

Who should read *Why Zebras Don’t Get Ulcers*?

This book suits anyone seeking to understand stress’s physiological impacts, including professionals in healthcare, psychology, or leadership roles. It’s also valuable for individuals managing anxiety, burnout, or chronic health issues linked to stress. Sapolsky’s accessible writing style appeals to both academic and general audiences.

Is *Why Zebras Don’t Get Ulcers* worth reading?

Yes—it’s a seminal work combining rigorous science with actionable insights. Sapolsky’s exploration of stress-related diseases (e.g., hypertension, immune dysfunction) and his humor make complex concepts engaging. The book remains widely cited in stress research and offers timeless strategies for mitigating modern stressors.

What causes stress-related ulcers in humans?

Unlike zebras facing short-term threats, humans experience chronic stress, which overactivates the sympathetic nervous system. This disrupts digestion, increases stomach acid production, and weakens protective mucosal lining, leading to ulcers. Prolonged cortisol exposure also suppresses immune responses that repair damaged tissue.

How does Sapolsky explain the “zebra metaphor”?

Zebras avoid ulcers because their stress (e.g., escaping lions) is brief and physical. Humans, however, endure psychological stressors (work deadlines, financial worries), triggering prolonged cortisol release. This mismatch between evolutionary biology and modern life exacerbates diseases like diabetes and depression.

What practical tips does the book offer for stress management?

Sapolsky recommends exercise, social connection, and mindfulness to reduce cortisol. He emphasizes regaining control over stressors, reframing negative thoughts, and prioritizing sleep. The book also advocates addressing systemic issues like poverty, which perpetuate chronic stress.

What are key quotes from *Why Zebras Don’t Get Ulcers*?

- **“We humans live well enough to generate stressors purely in our heads.”** Highlights how psychological stress differs from survival threats. - **“Chronic stress is not a disease—it’s a recipe for one.”** Underscores prolonged stress’s role in illness.

How does social hierarchy affect stress levels?

Sapolsky’s baboon research shows low-ranking individuals endure chronic stress due to social instability, increasing disease risk. Similarly, humans in marginalized groups or high-pressure jobs face comparable physiological tolls, linking social dynamics to health disparities.

なぜシマウマは胃潰瘍にならないのか

ストレス、ストレス関連疾患、およびコーピングに関する定評あるガイド

ロバート・サポルスキー

4.17(16602 Reviews)

『なぜシマウマは胃潰瘍にならないのか』の概要

日常的な不安が、なぜライオンから逃げるシマウマと同じ生物学的反応を引き起こすのか、その理由を探りましょう。長寿の専門家ピーター・アティアも推奨するサポルスキーの傑作は、現代のストレスがいかにして病気を生み出すのか、そしてこの破壊的なサイクルを断ち切るための実践的な解決策を明らかにしています。

語り方を選ぶ

1冊の本。さまざまな聴き方。

なぜシマウマは胃潰瘍にならないのかの同じアイデアを、あなたに合う声・深さ・ペースで学べます。いつでも切り替えられます。

第1章

When Stress Becomes Your Worst Enemy

Imagine your heart racing, palms sweating, and mind spiraling as you prepare for tomorrow's presentation. While you lie awake catastrophizing about potential humiliation, a zebra on the African savanna sleeps peacefully, unconcerned with performance anxiety or mortgage payments. This stark contrast forms the foundation of Robert Sapolsky's groundbreaking work on stress physiology. A Stanford neurobiologist who spent decades studying baboon troops in Kenya, Sapolsky combines rigorous science with disarming humor to explain why modern humans suffer from diseases our ancestors never experienced. Since its publication, "Why Zebras Don't Get Ulcers" has become required reading in medical schools worldwide, praised by figures from Bill Gates to Daniel Goleman, and established itself as the definitive layperson's guide to understanding the biology of stress. With over a million copies sold across multiple editions, this modern classic continues to influence how we think about the intersection of psychology and physical health.

第2章

The Fundamental Mismatch: Our Stone Age Bodies in a Modern World

The brilliance of Sapolsky's central insight lies in recognizing a fundamental mismatch between our physiological stress response and modern life. For zebras, stress means acute physical crises-sprinting away from a lion or, as a lion, chasing down dinner. Their bodies mobilize perfectly for these emergencies: energy pours from storage sites as glucose floods the bloodstream, heart rate and breathing accelerate, pain perception dulls, and senses sharpen. Meanwhile, long-term "building projects" like digestion, growth, tissue repair, and reproduction temporarily pause. Within minutes or hours, the zebra either resolves the crisis or dies, and its physiology returns to normal. Humans, however, generate a third category of stress-psychological and social disruptions that can persist for weeks, months, or years. We activate the same emergency response designed for immediate physical threats when worrying about mortgages, relationships, or career setbacks. Our sophisticated brains allow us to trigger full physiological stress responses through mere anticipation, turning on emergency systems and leaving them running indefinitely. This distinction explains why zebras don't get ulcers but humans do. The zebra's stress response perfectly manages short-term physical emergencies but becomes harmful when chronically activated. The price of this chronic activation includes energy depletion, cardiovascular damage, digestive disorders, growth inhibition, reproductive problems, immune suppression, and even brain cell damage. Hans Selye, a pioneer of stress physiology, accidentally discovered this phenomenon in the 1930s when his clumsy handling of laboratory rats produced peptic ulcers, enlarged adrenal glands, and shrunken immune tissues. When he ran a control group with the same handling stress but saline injections, they developed identical symptoms-revealing that the physical stress response itself was causing these changes.

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『なぜシマウマは胃潰瘍にならないのか』の一語一語が音声に合わせてリアルタイムでハイライトされ、自然に読み進められます。

第3章

The Orchestra of Stress: How Your Body Responds to Danger

Understanding stress requires appreciating how the brain regulates bodily functions. A mere thought-whether angry, sad, euphoric, or lustful-can trigger profound physiological changes without moving a muscle. You can make your pancreas secrete hormones, your liver produce enzymes, and alter blood flow throughout your body through pure thought. The autonomic nervous system works in opposition: sympathetic projections speed up the heart while parasympathetic projections slow it down. The sympathetic system diverts blood to muscles; the parasympathetic does the opposite. Having both active simultaneously would be like pressing the gas and brake together-a disaster the brain prevents by activating one branch while inhibiting the other. Beyond neural control, the brain mobilizes stress responses through hormone secretion. Scientists once believed peripheral glands like the pancreas and adrenals operated autonomously-a misconception that led to early 20th century "rejuvenation therapy" fads where aging men received testicular extracts from animals to combat aging. Eventually, scientists discovered the brain was the true master gland. The stress hormone cascade begins when the hypothalamus secretes CRH (corticotropin releasing hormone). Within fifteen seconds, CRH triggers the pituitary to release ACTH into the bloodstream, which then causes the adrenal glands to release glucocorticoids within minutes. Additional hormones activated during stress include epinephrine and norepinephrine (from the sympathetic nervous system), glucagon (which raises blood sugar), prolactin (which suppresses reproduction), endorphins (which blunt pain), and vasopressin (which affects cardiovascular response). Meanwhile, reproductive hormones, growth hormone, and insulin are inhibited. Importantly, the stress response isn't identical across all stressors or individuals. While males typically demonstrate a "fight-or-flight" response, females often exhibit a "tend and befriend" response involving oxytocin secretion, which promotes maternal behavior and social bonding. Different stressors produce distinct hormonal "signatures" that vary based on psychological context.

第4章

The Vulnerable Heart: How Stress Attacks Your Cardiovascular System

The cardiovascular stress response begins by increasing heart rate and blood pressure while strategically redistributing blood flow. Arteries to muscles dilate to increase energy delivery, while blood flow decreases dramatically to nonessential areas like the digestive tract and skin. The body also reduces blood flow to the kidneys and releases vasopressin to halt urine formation, conserving water for circulation. While this response is adaptive during genuine physical threats, it becomes maladaptive during psychological stress. When you're terrified and sprinting, increased blood flow to muscles matches metabolic demand. But when you're merely worrying about deadlines while sitting still, this same cardiovascular response becomes harmful. Chronic stress leads to hypertension through a vicious cycle: elevated blood pressure forces small vessels to develop thicker muscle layers, which increases vascular resistance, further raising blood pressure. This chronic hypertension damages the heart by causing left ventricular hypertrophy-a thickening of heart muscle that increases risk of irregular heartbeat. Blood vessels suffer as well, particularly at bifurcation points where vessels branch. These junctions are vulnerable to damage from increased pressure and turbulence. Once the smooth inner lining tears, inflammatory immune cells aggregate at the site along with fatty foam cells, forming atherosclerotic plaque. Heart disease often culminates in cardiac catastrophe during acute stress. A shocking piece of news can trigger fatal cardiac arrest within moments of the emotional surge. Strong emotions like anger double heart attack risk in the subsequent two hours. During the 1991 Persian Gulf War, more Israelis died from sudden cardiac death during SCUD missile attacks than from actual missile damage. Counterintuitively, extreme joy can kill just as effectively as extreme grief. Whether wailing in grief or leaping in ecstasy, the demands on a diseased heart remain dangerous. Your sympathetic nervous system affects coronary arteries similarly during murderous rage or thrilling orgasm. For the cardiovascular system, rage and ecstasy, grief and triumph all represent equivalent challenges to allostatic equilibrium.

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第5章

Energy Crisis: How Stress Disrupts Your Metabolism

During physical emergencies, your body must quickly access stored energy without time to digest food. Digestion breaks down complex food into simple building blocks: amino acids (from proteins), glucose (from carbohydrates), and fatty acids and glycerol (from fats). After a large meal, excess nutrients are stored-fatty acids combine with glycerol to form triglycerides in fat cells, glucose molecules link into glycogen chains in muscles and liver, and amino acids combine to form proteins throughout the body. During stress, this process reverses. First, sympathetic activation and parasympathetic suppression reduce insulin secretion. Second, glucocorticoids block nutrient transport into fat cells. Stress hormones trigger the breakdown of stored nutrients: triglycerides release fatty acids, glycogen degrades into glucose, and proteins convert back to amino acids. The liver transforms circulating amino acids into glucose through gluconeogenesis, making energy readily available. While this energy mobilization is essential during physical challenges, chronic activation causes problems similar to constantly withdrawing money with early withdrawal penalties. The process is inefficient-shuttling nutrients in and out of storage and powering enzymes to build and break down complex molecules requires energy, leading to everyday fatigue. Perpetually mobilized fat and glucose in the bloodstream increases atherosclerosis risk while raising "bad" LDL-cholesterol and decreasing "good" HDL-cholesterol. Chronic stress also promotes insulin resistance, particularly harmful for those with diabetes or pre-diabetic conditions. In adult-onset diabetes (type 2), the problem isn't too little insulin but cells failing to respond to it-insulin resistance. This typically occurs when fat cells become overstuffed as people age and gain weight. Chronic stress worsens this condition by mobilizing more glucose and fatty acids while promoting insulin resistance. Someone on the edge of becoming diabetic can be pushed over the threshold during periods of stress. This matters because adult-onset diabetes has reached epidemic proportions-increasing 33% among older adults and 70% among thirty-year-olds in just a decade. Even children now develop adult-onset diabetes more frequently than juvenile diabetes.

第6章

Digestive Distress: Your Gut Under Pressure

During stress, the body's digestive system undergoes a dramatic shutdown as the sympathetic nervous system takes control. This involves multiple simultaneous reactions: saliva production ceases, stomach acid secretion diminishes, and blood flow to digestive organs decreases by up to 80%. While this response was crucial for our ancestors facing immediate physical threats, it creates significant problems for modern humans experiencing chronic psychological stress. Even mild workplace anxiety can trigger these responses dozens of times daily. The fight-or-flight response can have particularly extreme manifestations in the digestive system. Under severe terror or panic, humans may experience spontaneous defecation-a primitive survival mechanism designed to shed unnecessary weight when fleeing predators. This occurs through a precise orchestration of the sympathetic nervous system, which simultaneously inhibits small intestine contractions while stimulating large intestine movement. What served as an adaptive response for our ancestors becomes a source of intense anxiety and embarrassment in modern contexts like public speaking or job interviews. The relationship between stress and food consumption follows a complex biochemical pattern. The immediate stress response triggers CRH release, which suppresses appetite within seconds. However, the slower-acting glucocorticoids, particularly cortisol, begin circulating within minutes and can persist for hours, stimulating appetite-especially for high-calorie comfort foods rich in fats and sugars. Modern life's constant low-grade stressors create a particularly problematic pattern: frequent CRH bursts throughout the day coupled with chronically elevated glucocorticoids. Research at major universities has demonstrated that individuals who secrete higher levels of glucocorticoids during stress are 75% more likely to overeat in the following hours and show particular cravings for sugary foods. Glucocorticoids' effects extend beyond immediate appetite stimulation to influence long-term fat storage patterns. These hormones specifically target abdominal "visceral" fat cells, which contain up to four times more glucocorticoid receptors than subcutaneous fat cells in other areas like the hips and thighs. This preferential targeting creates the characteristic "apple" body shape associated with chronic stress, rather than the less metabolically dangerous "pear" shape. Visceral fat cells are metabolically more active, readily releasing fatty acids directly to the liver where they're converted to glucose, promoting insulin resistance and increasing the risk of type 2 diabetes by up to 40%. Perhaps most concerning is the discovery of a self-reinforcing cycle between stress and eating patterns. Research from leading endocrinology centers has shown that consuming comfort foods actually reduces stress hormone production by up to 30%, while the accumulation of abdominal fat can dampen future stress responses through complex feedback mechanisms. This creates a powerful physiological and psychological cycle: stress promotes comfort eating and abdominal fat storage, which in turn provides temporary relief from stress, reinforcing the behavior. Breaking this cycle requires addressing both the underlying stress triggers and the established eating patterns simultaneously.

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『なぜシマウマは胃潰瘍にならないのか』の一語一語が音声に合わせてリアルタイムでハイライトされ、自然に読み進められます。

第7章

Growth Interrupted: How Stress Stunts Development

Growth transforms children's bodies comprehensively-brains enlarge, head shapes change, cells divide and synthesize proteins, cartilage at bone ends migrates into shafts and solidifies, baby fat converts to muscle, and puberty brings voice changes, body hair, and sexual development. This massive construction project requires substantial nutritional resources coordinated by various hormones, with growth hormone playing the central role. Stress inhibits skeletal growth because growing makes little evolutionary sense when you're fleeing danger. Stress dwarfism-though extremely rare-occurs in children subjected to severe psychological abuse or neglect. These children stop growing despite adequate nutrition and absence of disease. When removed from toxic environments before puberty, some "catch-up" growth occurs, though shortness and developmental issues often persist. Stress dwarfism involves extremely low growth hormone levels. In one remarkable case study, a hospitalized child's growth hormone levels doubled and growth rate tripled after forming an attachment with a nurse-then plummeted when she went on vacation, only to recover when she returned. This demonstrates how our emotional state directly affects cellular processes. Touch proves critical-rat pups separated from mothers show decreased growth hormone, but active stroking normalizes growth. Similarly, premature human infants who received just 45 minutes of daily touch grew 50% faster, matured more quickly, and left the hospital a week earlier than untouched infants. Childhood is when we form fundamental assessments about the world. Similarly, during fetal development, our bodies "learn" about the external environment and make lifelong physiological adaptations. When a fetus experiences stress, particularly nutritional deprivation, it develops a "thrifty" metabolism designed to store every bit of nutrition-leading to increased adult risks of hypertension, obesity, diabetes and cardiovascular disease. The Dutch Hunger Winter of WWII provides dramatic evidence: fetuses exposed to famine developed metabolic programming that increased disease risks decades later. Even within normal birth weights, lower weights correlate with higher metabolic syndrome risks. This relationship extends beyond nutrition to include stress hormones, as prenatal stress permanently increases glucocorticoid secretion and programs anxiety and cognitive changes.

第8章

Reproductive Shutdown: Sex and Stress Don't Mix

Stress profoundly disrupts our reproductive systems, causing irregular menstrual cycles, erectile difficulties, and decreased sexual interest. Erectile dysfunction is commonly triggered by stress, creating a vicious cycle of performance anxiety. Over half of male reproductive complaints stem from psychological rather than organic causes. While testosterone production must be severely compromised to affect fertility, even minor stress can completely disrupt erections. Female reproduction follows a hormonal cascade that stress disrupts through multiple mechanisms. When hunter-gatherer women breast-feed for brief periods every fifteen minutes around the clock for three years, prolactin levels remain elevated, suppressing ovulation. This pattern means hunter-gatherer women experience only about two dozen menstrual cycles in their lifetime, compared to hundreds for modern Western women. Stress disrupts female sexual desire just as it affects male erectile function. Both proceptive and receptive behaviors typically peak around ovulation but are suppressed during stress. This suppression stems from stress-reduced sex hormone secretion. Social subordination in female monkeys can suppress estrogen as effectively as ovariectomy, explaining how stress disrupts sexual behavior. The link between stress and miscarriage occurs through sympathetic nervous system activation. When stressed, norepinephrine and epinephrine dramatically decrease uterine blood flow, reducing oxygen delivery to the fetus. Studies across species show that psychological stressors cause this reduction in blood flow. While a single hypoxic episode is unlikely to cause harm, repeated episodes can lead to asphyxiation. Severe stress can therefore increase miscarriage risk, and at late pregnancy stages, elevated glucocorticoids from stress can trigger preterm birth. Despite these numerous mechanisms by which stress can disrupt reproduction, these systems are surprisingly resilient. Even in Nazi concentration camps where women endured starvation, slave labor and psychological terror, only 54% stopped menstruating-meaning reproductive physiology continued functioning in nearly half despite horrific conditions.

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第9章

The Compromised Defense: Stress and Your Immune System

The immune system's primary function is defending against infectious agents by distinguishing between "self" and "non-self" cells. This defense relies on white blood cells-lymphocytes (T and B cells) and monocytes. T cells provide cell-mediated immunity: when an invader enters the body, macrophages present it to T helper cells, triggering proliferation of cytotoxic killer cells that destroy the invader. B cells generate antibody-mediated immunity: after T helper cell activation, B cells produce antibodies with shapes specifically matching invader features, immobilizing and targeting them for destruction. Stress disrupts numerous immune functions: it suppresses lymphocyte formation and circulation, inhibits antibody production against infections, disrupts communication between lymphocytes, and dampens inflammation. Glucocorticoids are the primary mediators, causing thymus shrinkage by halting new lymphocyte formation, inhibiting immune messenger release, removing lymphocytes from circulation, and even triggering lymphocyte suicide through programmed cell death pathways. Contrary to traditional understanding, stress initially enhances immunity during the first thirty minutes (phase A), particularly innate immunity. During this subtle rise in glucocorticoid levels at the start of phase B, these hormones don't indiscriminately kill lymphocytes but selectively eliminate older, less effective ones-essentially sculpting the immune response. Additionally, glucocorticoids and epinephrine divert many lymphocytes to infection sites rather than deactivating them. With truly major stressors, immunity drops below baseline. This pattern explains why autoimmune diseases present a paradox: while massive glucocorticoid doses suppress symptoms, stress often worsens these conditions. Two scenarios increase autoimmunity risk: numerous transient stressors that ratchet the system upward, and having phase A without adequate phase B. The connection between stress and susceptibility to colds has strong scientific support. In landmark research, volunteers were housed under controlled conditions, assessed for stress levels, then exposed to identical amounts of rhinovirus. Results showed stressed individuals were three times more likely to develop colds, with prolonged social stressors beyond one month creating the greatest risk.

第10章

The Mind-Body Connection: Why Psychological Stress Feels Physical

The stress field underwent a dramatic transformation when bioengineers brought mathematical precision to understanding stress responses. They revealed the system's remarkable sensitivity to stressor intensity, demonstrating linear relationships between physiological disruptions and hormone responses. This mechanistic approach seemed to promise perfect predictability-measure the disruption, calculate the response. Then came a revolutionary discovery: psychological factors could modulate these responses. A child experiencing pain showed less stress when comforted by their mother, despite identical physical stimuli. This revelation led to understanding that psychological variables could not only modify stress responses but trigger them entirely without physical stressors. Jay Weiss at Rockefeller University conducted elegant experiments identifying key psychological variables in stress responses. His studies revealed several critical factors: outlets for frustration (like rats gnawing on wood during electric shocks) significantly reduce stress effects; social support networks dramatically decrease stress responses; predictability makes stressors less damaging; and perhaps most importantly, control-or even just the perception of control-powerfully modulates stress responses. Another critical psychological variable affects stress responses: the perception that things are worsening. In experiments, rats experiencing an increase in electric shocks develop hypertension, while rats experiencing a decrease don't, despite facing identical conditions. This principle appears in human illness too-parents of children with cancer in remission show only moderate glucocorticoid increases despite a 25% mortality risk, because this represents dramatic improvement from previous odds. The psychological factors triggering stress responses-loss of control or predictability, lack of outlets for frustration or social support, and perceptions of worsening conditions-often overlap and sometimes conflict. When variables conflict, their relative power determines the outcome. Unexpectedly winning the lottery might be stressful due to unpredictability, but the perception of improvement usually outweighs this.

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『なぜシマウマは胃潰瘍にならないのか』の一語一語が音声に合わせてリアルタイムでハイライトされ、自然に読み進められます。

第11章

Managing the Beast: Effective Strategies for Handling Stress

Despite all the bad news about stress's harmful effects, there is hope. Not everyone collapses under stress-some individuals cope remarkably well. The key insight comes from gerontology research showing that while average measures of health decline with age, the variability increases dramatically. Among elderly populations, some individuals actually improve on certain health metrics with age. In a classic 1960s study, psychiatrists examined parents of children dying from cancer and found significant variance in their glucocorticoid levels. Parents with lower stress hormones displayed specific coping mechanisms: they could displace major worries onto less threatening concerns, practice selective denial during remission periods, and use religious rationalization to find meaning in their child's illness. These psychological strategies effectively reduced their physiological stress responses during an unimaginably difficult situation. While some individuals naturally excel at coping with stress, the good news is that we can all change our coping styles. Physical conditioning through exercise improves cardiovascular health, psychotherapy can alter both behaviors and physiological markers in Type-A personalities, and relaxation techniques can modulate pain responses. Exercise counters stress by decreasing risk of metabolic and cardiovascular diseases, improving mood through beta-endorphin secretion, creating a sense of self-efficacy, and providing an appropriate outlet for the stress response's muscular preparation. However, important qualifications apply: exercise only enhances mood for hours to a day afterward; it must be voluntary rather than forced; aerobic exercise provides better health benefits than anaerobic; it requires regular sessions of at least 20-30 minutes several times weekly; and excessive exercise can be harmful. Regular meditation practice (approximately daily sessions of 15-30 minutes) appears beneficial for health, reducing glucocorticoid levels and sympathetic tone. Social support isn't always straightforward as a stress reducer, but one of the strongest stress-reducing aspects of social support is actually giving it rather than receiving it-making the world better one act at a time provides a powerful sense of control in an uncontrollable world. Different coping styles work better in different circumstances. Problem-solving approaches are appropriate before challenges, while emotion-focused reframing works better after unavoidable negative outcomes. The key is developing cognitive flexibility to switch strategies when current approaches aren't working, rather than doubling down on ineffective methods. The 80/20 rule applies powerfully to stress management: 80 percent of stress reduction comes from the first 20 percent of effort. The critical step is genuinely deciding to change-not because others pressure you, but because you've truly committed. Once you've made that decision, even imperfect techniques can work wonders. Taking time almost daily for stress management demonstrates you've made change important enough to say no to competing demands. The key principles of effective stress management include: In truly terrible situations beyond control, denial can be adaptive, while lesser problems require balanced, protective hope; seek control over present stressors but accept what's already happened and what's truly uncontrollable; pursue predictable, accurate information when timely and manageable; find regular, benign outlets for frustrations; and develop genuine social affiliation and support beyond mere socializing. While not all health problems are stress-related, our psychological outlook significantly influences many aspects of health and disease.

★★★★★

『なぜシマウマは胃潰瘍にならないのか』を最後まで読み終えました

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『なぜシマウマは胃潰瘍にならないのか』の主要テーマ

stress physiology
chronic stress management
evolutionary mismatch
psychosomatic medicine
cortisol and glucocorticoids

『なぜシマウマは胃潰瘍にならないのか』の名言

Humans generate psychological and social disruptions that can persist for weeks, months, or years.
The zebra's stress response becomes harmful when chronically activated.
You can alter blood flow throughout your body through pure thought.
The brain was the true master gland.
Extreme joy can kill just as effectively as extreme grief.

『なぜシマウマは胃潰瘍にならないのか』の登場人物

Robert M. SapolskyAuthor and Stanford neurobiologist
Hans SelyePioneer of stress physiology

著者について

『なぜシマウマは潰瘍にならないのか（Why Zebras Don’t Get Ulcers）』の著者であり、マッカーサー財団の「天才賞」受賞者でもあるロバート・M・サポルスキーは、スタンフォード大学の生物学・神経学・脳神経外科学教授であり、その研究は神経科学、ストレス研究、進化生物学の架け橋となっています。

神経内分泌学の先駆者であるサポルスキーが、ケニアで野生のヒヒを数十年にわたって調査したフィールドワークは、ストレス関連疾患に関する画期的な知見をもたらし、その詳細は科学的名著である本書に記されています。彼の専門知識は、脳の老化に対するグルココルチコイドの影響、神経保護のための遺伝子治療、そして人間行動の生物学的根拠にまで及びます。

サポルスキーの他の主要な著作には、『Behave: The Biology of Humans at Our Best and Worst』（ニューヨーク・タイムズ紙ベストセラー）や、ベイエリア書評家賞を受賞した『A Primate’s Memoir』などがあります。『ザ・ニューヨーカー』、『ディスカバー』、『ウォール・ストリート・ジャーナル』などの各誌に頻繁に寄稿しており、科学に関する優れた執筆活動に贈られるルイス・トマス賞を受賞しました。1994年の初版以来、改訂を重ねてきた『なぜシマウマは潰瘍にならないのか』は、現在も重要な文献であり続け、10以上の言語に翻訳され、学術界や公衆衛生の分野で広く引用されています。

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"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."

@Raaaaaachelw

"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."

@Matt, YC alum

108

"Reading used to feel like a chore. Now it’s just part of my lifestyle."

@Erin, Investment Banking Associate , NYC

254

"Feels effortless compared to reading. I’ve finished 6 books this month already."

@djmikemoore

"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

@Pitiful

4.5K

"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."

@SofiaP

"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"

@Jaded_Falcon

201

"It is great for me to learn something from the book without reading it."

@OojasSalunke

"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."

@Leo, Law Student, UPenn

483

"Makes me feel smarter every time before going to work"

@Cashflowbubu

BeFreedがウェブ上でどのように話題になっているかをもっと見る

コロンビア大学卒業生がサンフランシスコで開発

LOVED BY

1,000,000+ curious minds.

4.7

avg rating

1M+ learners

"Instead of endless scrolling, I just hit play on BeFreed. It saves me so much time."

@Moemenn

"I never knew where to start with nonfiction—BeFreed’s book lists turned into podcasts gave me a clear path."

@Chloe, Solo founder, LA

117

"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."

@Raaaaaachelw

"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."

@Matt, YC alum

108

"Reading used to feel like a chore. Now it’s just part of my lifestyle."

@Erin, Investment Banking Associate , NYC

254

"Feels effortless compared to reading. I’ve finished 6 books this month already."

@djmikemoore

"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

@Pitiful

4.5K

"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."

@SofiaP

"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"

@Jaded_Falcon

201

"It is great for me to learn something from the book without reading it."

@OojasSalunke

"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."

@Leo, Law Student, UPenn

483

"Makes me feel smarter every time before going to work"

@Cashflowbubu

"Instead of endless scrolling, I just hit play on BeFreed. It saves me so much time."

@Moemenn

"I never knew where to start with nonfiction—BeFreed’s book lists turned into podcasts gave me a clear path."

@Chloe, Solo founder, LA

117

"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."

@Raaaaaachelw

"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."

@Matt, YC alum

108

"Reading used to feel like a chore. Now it’s just part of my lifestyle."

@Erin, Investment Banking Associate , NYC

254

"Feels effortless compared to reading. I’ve finished 6 books this month already."

@djmikemoore

"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

@Pitiful

4.5K

"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."

@SofiaP

"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"

@Jaded_Falcon

201

"It is great for me to learn something from the book without reading it."

@OojasSalunke

"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."

@Leo, Law Student, UPenn

483

"Makes me feel smarter every time before going to work"

@Cashflowbubu

"Instead of endless scrolling, I just hit play on BeFreed. It saves me so much time."

@Moemenn

"I never knew where to start with nonfiction—BeFreed’s book lists turned into podcasts gave me a clear path."

@Chloe, Solo founder, LA

117

"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."

@Raaaaaachelw

"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."

@Matt, YC alum

108

"Reading used to feel like a chore. Now it’s just part of my lifestyle."

@Erin, Investment Banking Associate , NYC

254

"Feels effortless compared to reading. I’ve finished 6 books this month already."

@djmikemoore

"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

@Pitiful

4.5K

"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."

@SofiaP

"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"

@Jaded_Falcon

201

"It is great for me to learn something from the book without reading it."

@OojasSalunke

"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."

@Leo, Law Student, UPenn

483

"Makes me feel smarter every time before going to work"

@Cashflowbubu

BeFreedがウェブ上でどのように話題になっているかをもっと見る

今すぐ学習の旅を始めよう

第11章

なぜシマウマは胃潰瘍にならないのか

概要『なぜシマウマは胃潰瘍にならないのか』の概要

1冊の本。さまざまな聴き方。

When Stress Becomes Your Worst Enemy

The Fundamental Mismatch: Our Stone Age Bodies in a Modern World

聴きながら、すべての言葉を目で追えます

The Orchestra of Stress: How Your Body Responds to Danger

The Vulnerable Heart: How Stress Attacks Your Cardiovascular System

『なぜシマウマは胃潰瘍にならないのか』をもっと深く楽しむ

Energy Crisis: How Stress Disrupts Your Metabolism

Digestive Distress: Your Gut Under Pressure

聴きながら、すべての言葉を目で追えます

Growth Interrupted: How Stress Stunts Development

Reproductive Shutdown: Sex and Stress Don't Mix

『なぜシマウマは胃潰瘍にならないのか』をもっと深く楽しむ

The Compromised Defense: Stress and Your Immune System

The Mind-Body Connection: Why Psychological Stress Feels Physical

聴きながら、すべての言葉を目で追えます

Managing the Beast: Effective Strategies for Handling Stress

『なぜシマウマは胃潰瘍にならないのか』を最後まで読み終えました

『なぜシマウマは胃潰瘍にならないのか』の主要テーマ

『なぜシマウマは胃潰瘍にならないのか』の名言

『なぜシマウマは胃潰瘍にならないのか』の登場人物

著者について

なぜシマウマは胃潰瘍にならないのかの要約をダウンロード

他のユーザーのお気に入り

この本に関するよくある質問

What is Why Zebras Don't Get Ulcers about?

Who should read Why Zebras Don’t Get Ulcers?

Is Why Zebras Don’t Get Ulcers worth reading?

What causes stress-related ulcers in humans?

この学習プランの一部

Learn about biological trauma

もっと見る

1,000,000+ curious minds.

1,000,000+ curious minds.

1冊の本。さまざまな聴き方。

When Stress Becomes Your Worst Enemy

The Fundamental Mismatch: Our Stone Age Bodies in a Modern World

聴きながら、すべての言葉を目で追えます

The Orchestra of Stress: How Your Body Responds to Danger

The Vulnerable Heart: How Stress Attacks Your Cardiovascular System

『なぜシマウマは胃潰瘍にならないのか』をもっと深く楽しむ

Energy Crisis: How Stress Disrupts Your Metabolism

Digestive Distress: Your Gut Under Pressure

聴きながら、すべての言葉を目で追えます

Growth Interrupted: How Stress Stunts Development

Reproductive Shutdown: Sex and Stress Don't Mix

『なぜシマウマは胃潰瘍にならないのか』をもっと深く楽しむ

The Compromised Defense: Stress and Your Immune System

The Mind-Body Connection: Why Psychological Stress Feels Physical

聴きながら、すべての言葉を目で追えます

Managing the Beast: Effective Strategies for Handling Stress

『なぜシマウマは胃潰瘍にならないのか』を最後まで読み終えました

他のユーザーのお気に入り

この学習プランの一部

Learn about biological trauma

もっと見る

『なぜシマウマは胃潰瘍にならないのか』の概要