What is *Hacking Darwin* by Jamie Metzl about?

*Hacking Darwin* explores the genetic engineering revolution and its ethical implications for humanity’s future. Jamie Metzl examines CRISPR technology, embryo selection, and gene editing’s potential to eradicate diseases or create genetic disparities. The book connects historical evolutionary biology with emerging tech trends, warning of a possible genetic arms race while advocating for global ethical frameworks.

Who should read *Hacking Darwin*?

This book is essential for futurists, bioethicists, policymakers, and anyone interested in biotechnology’s societal impacts. Readers of *Homo Deus* or *The Gene* will appreciate its interdisciplinary approach blending science, ethics, and geopolitics.

Is *Hacking Darwin* worth reading in 2025?

Yes—Metzl’s 2019 predictions about accelerating gene-editing advancements remain critically relevant. The book’s analysis of CRISPR, designer babies, and longevity research provides foundational knowledge for navigating today’s debates about AI-aided genetic engineering and equitable access to biotech.

What are the main ethical concerns in *Hacking Darwin*?

Metzl highlights risks like genetic inequality, unintended mutations, and state-sponsored eugenics programs. He argues uncontrolled editing could create a “genetic underclass” while emphasizing the need for international oversight to prevent exploitation.

How does *Hacking Darwin* explain CRISPR technology?

CRISPR is presented as a revolutionary gene-editing tool enabling precise DNA modifications. Metzl details its applications in curing genetic diseases, enhancing physical traits, and potentially extending human lifespans, while cautioning about its military and commercial misuse.

What is Jamie Metzl’s background in genetics?

Metzl holds a Ph.D. in Southeast Asian history from Oxford but has advised the WHO on genome editing and served as a biotechnology executive. His expertise combines geopolitical strategy with scientific literacy, validated by his Atlantic Council and Singularity University roles.

How does *Hacking Darwin* compare to *Homo Deus*?

While Yuval Harari’s *Homo Deus* speculates broadly about post-human futures, Metzl’s work focuses specifically on genetic engineering’s near-term implications. Both books critique unchecked technological power, but *Hacking Darwin* offers concrete policy recommendations for biotech governance.

What solutions does Metzl propose for regulating genetic engineering?

He advocates for a global regulatory body similar to the IAEA, transparent public-private research partnerships, and ethical guidelines prioritizing health equity over enhancement. Metzl stresses the urgency of preemptive action before technologies become weaponized.

ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める

遺伝子工学と人類の未来

ジェイミー・メッツル

3.98(3726 Reviews)

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』の概要

遺伝子工学は人類の未来を塗り替えようとしています。『ハッキング・ダーウィン（Hacking Darwin）』の中で、ジェイミー・メッツルは私たちの生物学的進化の次なる境地を探求しており、シッダールタ・ムカジーはこれを「画期的」と称賛しています。私たちが子供をデザインできるようになったとき、何が起こるのでしょうか？2019年のノミネート作である本書は、人間であることについての私たちの最も深い信念に挑みます。

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1冊の本。さまざまな聴き方。

ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決めるの同じアイデアを、あなたに合う声・深さ・ペースで学べます。いつでも切り替えられます。

第1章

The Genetic Revolution Is Here, Whether We're Ready Or Not

Jamie Metzl's "Hacking Darwin" has been called "required reading for anyone who wants to understand the future of humanity" by Bryan Johnson, founder of Kernel and OS Fund. This groundbreaking exploration of genetic engineering's impact on human evolution has captivated readers from Silicon Valley to academia, appearing on Bill Gates' recommended reading list and sparking intense debate in scientific circles. Beyond its scientific impact, the book has become a cultural touchstone in discussions about humanity's future, with tech luminaries like Ray Kurzweil praising its balanced approach to both the promises and perils of genetic technologies.

第2章

Darwin's Rules Are Changing

For 3.8 billion years, life on Earth has followed Darwin's rules: random mutation and natural selection. Sexual reproduction supercharged this process 540 million years ago, combining genetic material from two parents to create unprecedented diversity. This evolutionary system produced everything from dinosaurs to humans through countless genetic experiments, with each generation slightly different from the last. But now, we stand at a revolutionary turning point. Our species is about to begin evolving by an entirely different set of rules. From this moment forward, our mutations will no longer be random but self-designed. Our selection will no longer be natural but self-directed. We are beginning to hack Darwin. This transformation isn't science fiction. Unlike Jules Verne's moon landing fantasy of 1865, we're at the equivalent of 1962 when Kennedy announced the Apollo mission-the foundational technology already exists. The genetic revolution isn't speculative; it's the logical extension of tools we're already using. The only variables are timing and what values will guide us. As we increasingly understand our biology as information technology-code that can be read, written, and hacked-we'll have the same expectations for ourselves as for our devices. Using IVF and embryo selection, we'll soon routinely screen out genetic diseases and select broader traits. Eventually, technologies like CRISPR will allow precise genetic alterations, potentially introducing DNA from other humans, animals, or synthetic sources. Over time, conception through sex may be seen as unnecessarily risky. Governments and insurance companies will encourage IVF to avoid expensive genetic diseases. Despite the jarring nature of this transformation, our species will inevitably pursue technologies that eradicate diseases and extend lifespans. The fundamental questions we face are profound: Will we use these technologies to expand or limit humanity? Will benefits go only to the privileged few? Who has the right to make decisions affecting the human gene pool? Every human needs to participate in answering these questions, educating ourselves on the issues at stake.

聴きながら、すべての言葉を目で追えます

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』の一語一語が音声に合わせてリアルタイムでハイライトされ、自然に読み進められます。

第3章

Reading Our Genetic Code

Our DNA is made up of four nucleotides (G, A, T, C) arranged in specific sequences that form genes, which provide instructions for making proteins. These genes are packaged into 23 pairs of chromosomes, with humans having about 21,000 genes and 3.2 billion base pairs. While protein-coding genes are crucial, nearly 99% of DNA is non-coding, regulating how genes are expressed rather than being "junk" as once thought. The Human Genome Project, completed in 2003 after 13 years and $2.7 billion, marked a breakthrough in reading our genetic code. Since then, sequencing technology has advanced dramatically, with costs plummeting from billions to hundreds of dollars. Today, a full genome sequence takes about a day and costs around $700, with $100 genomes on the horizon. Scientists have made tremendous progress understanding genetic diseases, particularly those caused by single-gene mutations like Tay-Sachs, cystic fibrosis, and Huntington's. While these diseases are individually rare, genetic screening has proven effective in prevention, as demonstrated by the Jewish community's successful campaign against Tay-Sachs. The revolution in genetic analysis paired with in vitro fertilization has transformed human reproduction. Starting with Samuel Schenk's 1878 discovery of egg fertilization in glass dishes and culminating in the birth of Louise Brown, the first "test-tube baby," in 1978, IVF opened new possibilities for applying genetic knowledge to human reproduction. Despite initial controversy-with Catholic theologians calling it "unnatural" and a "moral abomination," medical associations opposing it as too aggressive, and the Browns receiving hate mail with plastic fetuses-IVF gradually became normalized. Scientists soon developed preimplantation genetic testing (PGT), which screens embryos before implantation for chromosomal abnormalities and genetic diseases. Initially used to prevent miscarriages and test for a small number of single-gene disorders, PGT now screens for thousands of genetic conditions. As screening technology improves and costs decrease, parents will increasingly weigh conception through sex against IVF with genetic screening. Just as parents take precautions like vaccination to protect their children, genetic screening may become viewed as responsible parenting.

第4章

The Future of Human Reproduction

The growing acceptance of IVF and preimplantation genetic testing is gradually shifting how we view human reproduction. As the cost of treating genetic diseases ($600,000 lifetime for cystic fibrosis) is weighed against prevention through embryo screening, economic incentives are aligning with health outcomes. By 2035, parents using IVF and preimplantation embryo selection will face difficult choices. The doctor might explain how genetic screening capabilities have expanded beyond single-gene disorders to complex polygenic traits. While still probabilistic rather than deterministic, these screenings can predict likelihood of diseases like Alzheimer's, heart conditions, and cancers. The most uncomfortable revelation might come with IQ and personality trait screening. Despite hesitation about reducing human identity to genetic probabilities, parents could be confronted with compelling statistics about correlations between IQ and life outcomes. The doctor might carefully present these options without judgment, leaving parents torn between embracing genetic optimization and preserving life's mysteries. By 2045, reproduction could be radically transformed. Instead of invasive egg retrieval, a simple blood draw might collect the necessary biological material. This advancement, based on stem cell technology, would allow busy professionals to integrate genetic selection and reproduction into their everyday lives without disruption-beginning a new era where traditional conception methods become increasingly optional rather than necessary. The process would convert blood cells into induced pluripotent stem cells (iPSCs), which could then be transformed into hundreds or thousands of eggs, offering vastly more genetic options than traditional IVF's limited egg retrieval. This revolutionary potential of stem cells began unfolding in 1981 when British researchers first extracted stem cells from mouse embryos, with human embryonic stem cells following in 1998. The real breakthrough came when Shinya Yamanaka discovered that just four "master genes" could transform any adult cell back into a stem cell. This discovery, building on John Gurdon's earlier work showing cells could be developmentally reprogrammed, earned them the 2012 Nobel Prize. Yamanaka's induced pluripotent stem cells revolutionized biology by demonstrating that the biological clock could tick backward, allowing specialized cells to revert to their embryonic potential. By 2012, Japanese scientists had used Yamanaka factors to transform mouse skin cells into egg and sperm progenitor cells, which developed into functional eggs and sperm capable of producing healthy offspring. By 2014, scientists in England and Israel replicated this with human cells, and by 2018, researchers had induced egg precursor cells from human blood.

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

毎日の新しい気づきを10万件以上のレッスンから
言葉をハイライトして音声と同期
ライブラリを保存して、どの端末からでも利用

第5章

Decoding Complex Human Traits

The genetic revolution has provided us with unprecedented insights into human biology that our ancestors could never have imagined. Yet even our seemingly straightforward genetic diseases should inspire profound humility. While scientists have successfully linked single gene mutations to specific conditions like cystic fibrosis or Huntington's disease, the reality proves far more intricate. Some individuals carry these supposedly deterministic mutations without developing symptoms, potentially protected by other genes or environmental factors that we're only beginning to understand. Our genetics operate within a sophisticated orchestra of multiple interacting biological systems - the epigenome that regulates gene expression, the transcriptome that represents actively expressed genes, the proteome comprising all proteins, the metabolome tracking biochemical processes, the microbiome of symbiotic organisms, and the virome of viral inhabitants. These systems function within varied environmental contexts, creating layers of complexity that far exceed our initial expectations. Despite early euphoria following the Human Genome Project, scientists now recognize that merely collecting genetic data doesn't automatically translate to understanding its functional significance. To tackle this genetic complexity, researchers study simpler, faster-breeding model organisms that share our evolutionary heritage. Humans share approximately 60% of DNA with fruit flies (having diverged 700 million years ago) and 92% with mice (split 80 million years ago). These evolutionary relatives serve as crucial experimental subjects - from early radiation exposure studies to modern CRISPR gene editing - helping researchers understand fundamental biological systems and disease mechanisms. For instance, fruit flies have helped identify genes involved in circadian rhythms, while mice models have revolutionized cancer research. Genome-wide association studies (GWAS) have emerged as a powerful tool, analyzing hundreds of thousands or millions of genetic variations across diverse populations to identify patterns linked to specific traits or diseases. Rather than examining single mutations, this process digitally scans genomes for statistically significant variations across large groups, revealing complex genetic architectures underlying conditions like type 2 diabetes, schizophrenia, and height. Next-generation sequencing technologies examine either protein-coding genes (exome sequencing) or entire genomes, providing increasingly detailed information about genetic patterns and rare variants. As we transition from simple single-gene causality to complex genetic networks, artificial intelligence becomes essential for analysis. The ancient Chinese game Go perfectly demonstrates how AI revolutionizes complex pattern recognition. While IBM's Deep Blue defeated chess champion Garry Kasparov in 1996, Go's vastly greater complexity seemed beyond computational reach. Yet Google DeepMind's AlphaGo defeated world champions, and its successor AlphaGo Zero surpassed this achievement after just three days of self-play, demonstrating the power of machine learning in mastering complex patterns. This revolutionary pattern-recognition capability is transforming genetic research and medicine. Companies like Deep Genomics are merging AI and genomics because "biology is too complex for humans to understand" without computational assistance. Major players including Google, WuXi NextCODE, and Biogen are deploying sophisticated machine learning systems to analyze massive genetic datasets, identify disease patterns, and predict drug responses. These tools are beginning to unlock the complex relationships between genetic variations and human traits, promising more precise diagnostic tools and personalized treatment approaches.

第6章

Understanding Nature vs. Nurture

As we develop increasingly sophisticated genetic understanding, we confront fundamental questions about human identity. The age-old nature versus nurture debate now has unprecedented stakes as we gain power to select embryos based on genetic profiles. Our forebears have debated this for millennia-from Plato believing humans are born with innate knowledge to Aristotle arguing knowledge is acquired. Today, most agree the answer is "both"-nature and nurture are dynamic systems continually interacting. This isn't just philosophical; if we're mostly nature, fixing problems requires genetic intervention. If mostly nurture, environmental changes would be more appropriate. Twin studies provide crucial insights. Identical twins separated at birth share remarkable similarities-from schizophrenia rates to personality traits and habits. Thomas Bouchard's multidecade study found identical twins raised separately had about the same chance of sharing traits as those raised together. A massive 2015 meta-analysis of twin studies concluded humans are about half defined by genetics, with some traits being more heritable than others. Height exemplifies a predominantly genetic trait that can still be influenced by environment. North Koreans who grew up during the 1990s famine are up to three inches shorter than their South Korean counterparts, showing how malnutrition can override genetic potential. Experts estimate 60-80% of height differences between people are genetic. Stephen Hsu's groundbreaking research using 500,000 sequenced genomes from the UK Biobank demonstrated how height can be predicted from genetics alone-achieving accuracy within about an inch. This opens doors to understanding, predicting, and potentially selecting for other complex traits and diseases once sufficient genomic data is available. Intelligence, among our most complex traits, presents even greater challenges. Despite controversy, twin studies consistently show intelligence is largely genetic and heritable. The Minnesota Twin Family Study found 70% of IQ was based on genetics, with only 30% from different life experiences. More recent reviews estimate IQ to be about 60% heritable, with genetic influence increasing as people age. Environmental factors still matter significantly-Eric Turkheimer found genetic predictors less accurate for children from disadvantaged families, suggesting negative environmental factors have greater relative impact in those situations.

聴きながら、すべての言葉を目で追えます

第7章

The CRISPR Revolution

Revolutionary ideas and technologies advance together, from Mendel's pea experiments to modern genetic engineering. This coevolution shifts our self-perception from divine creation to genetic code. Scientists have progressed from crude radiation-induced mutations to increasingly precise gene editing techniques. Gene editing evolved rapidly from zinc-finger nucleases (ZFN) in 2009 to transcription activator-like effector nucleases (TALENs) in 2011. While ZFN could precisely cut DNA at specific locations, TALENs offered greater flexibility and versatility. Both technologies, however, would soon be overshadowed by an even more revolutionary tool. CRISPR originated from bacteria's billion-year battle with viruses. In 1987, Japanese researchers noticed repeating code clusters in bacterial DNA. Spanish researcher Francisco Mojica later recognized these clusters matched viral code sequences, suggesting they functioned as a bacterial immune system. Dutch researcher Ruud Jansen named these sequences "clustered regularly interspaced short palindromic repeats" (CRISPR). In 2010-2012, researchers including Sylvain Moineau, Emmanuelle Charpentier, Jennifer Doudna, and Martin Jinek transformed CRISPR from a bacterial defense mechanism into a precise gene-editing tool. They discovered how CRISPR-Cas9 could make predictable DNA breaks and be adapted to edit any genetic sequence. By 2013, Doudna, Charpentier, and Feng Zhang demonstrated CRISPR could target multiple locations in the human genome simultaneously. Unlike previous techniques requiring months of design, CRISPR systems could be deployed in days at minimal cost, using the same "scissors" bacteria use against viruses to snip and potentially insert genetic code at targeted locations. CRISPR applications have already reached consumers through products like non-browning Arctic apples, virus-resistant Rainbow papayas, bruise-resistant Innate potatoes, and Del Monte's lycopene-enhanced pink pineapples. Scientists are developing waxy corn for better cornstarch, wheat with higher fiber and lower gluten, climate-resistant tomatoes, and camelina with enhanced omega-3 fatty acids. One of the most promising gene therapies is CAR-T, where T cells are extracted from cancer patients, genetically enhanced to express chimeric antigen receptors, and reintroduced to fight cancer with new powers. Novartis's 2017 trials showed 83% of patients experiencing significant cancer remission within three months. The stream of CRISPR breakthroughs accelerates yearly: repairing cystic fibrosis defects in human stem cells (2013), correcting liver cells in mice with hereditary tyrosinemia (2014), editing beta-globin genes to address thalassemia (2015), extracting HIV from human immune cells (2016), correcting embryonic heart defect genes (2017), addressing Duchenne muscular dystrophy mutations (2018), and precisely editing sickle cell mutations (2019).

第8章

The Quest for Immortality

Humans have always struggled with mortality. From Gilgamesh's quest for immortality to Methuselah's legendary 969-year lifespan, cultures throughout history have sought ways to extend life. While early attempts like Serge Voronoff's bizarre monkey testicle transplants in the 1920s failed, human lifespan has increased dramatically through advances in healthcare, sanitation, and nutrition-from an average of 47 years in the US in 1900 to 79 today. To push these boundaries further, scientists must understand aging itself-a complex process involving multiple bodily systems deteriorating at different rates. Aging defies simple definition because it's not one process but many systems decaying at different rates. Scientists variously define it as changes making organisms more likely to die, progressive functional decline, increased inflammation, oxidative damage, or diminished stem cell activation. Evolution doesn't particularly care how long we live beyond our reproductive years. While babies and parents are essential to human evolution, grandparents historically were less so. This gives us hope for extending lifespan, as we're not pushing against strongly selected evolutionary traits. Calorie restriction (CR) consistently extends lifespan in various organisms from yeast to mammals. Studies with macaque monkeys showed 15% calorie reduction translated to living three years longer with better health. The CALERIE study with humans demonstrated 15% calorie reduction produced 10% lower metabolism-suggesting less cellular wear and tear that might extend lifespan. Jeanne Calment, who lived to 122 while eating two pounds of chocolate daily and riding her bicycle until 100, represents the current upper limit of human lifespan. Researchers like Nir Barzilai study supercentenarians to identify genetic factors enabling extreme longevity. His research with Ashkenazi Jewish centenarians reveals these individuals don't just live longer but remain healthier longer, with compressed periods of illness at life's end. Cells must constantly choose between allocating energy to growth or repair. Young organisms have high metabolism for growth, but this "full throttle" approach wears out cells. In times of scarcity, cells shift to repair mode by regulating glucose uptake. Studies show that when roundworms, fruit flies, and mice shift from growth to repair mode, they live longer, healthier lives. Rapamycin, discovered in Easter Island soil bacteria, regulates cellular metabolism by targeting the mTOR protein. Studies show rapamycin extends lifespan by about 25% across multiple species from yeast to rats. However, its immune-suppressing effects cause concerning side effects like anemia and cataracts. Companies like Novartis and resTORbio are racing to develop rapamycin derivatives that maximize benefits while minimizing risks.

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

毎日の新しい気づきを10万件以上のレッスンから
言葉をハイライトして音声と同期
ライブラリを保存して、どの端末からでも利用

第9章

Ethical Challenges of the Genetic Revolution

How we apply the powerful tools of the genetic revolution will significantly determine humanity's future. The ethical challenges are immense, with no easy answers to questions of complexity, responsibility, diversity, and equity. Human genetics presents extraordinary complexity-genes perform multiple functions and interact in ways we don't fully understand. The sickle cell mutation illustrates this complexity: harmful in double copies but potentially beneficial against malaria in single copies. Eliminating it could solve one problem while creating others, potentially requiring cascading interventions like gene drives against mosquitoes, which could crash ecosystems. Critics warning of "slippery slopes" in genetic modification aren't wrong-each small step justifies the next. If we accept mitochondrial donation to prevent disease, why not other heritable changes? If selecting embryos to prevent Huntington's disease is acceptable, why not select for longevity? The dark cloud of eugenics hangs over human genetic engineering. From ancient infanticide to Victorian-era "scientific" breeding programs, humans have long practiced selective reproduction. After Darwin's theories emerged, his cousin Francis Galton developed eugenics theories promoting "race-betterment" through selective breeding. American progressives embraced these ideas, believing science could create better societies by preventing "defective" births. By 1927, thirty U.S. states had passed sterilization laws, with the Supreme Court ruling them constitutional in Buck v. Bell. Nazi Germany, watching closely, expanded these concepts into their racial hygiene programs, starting with sterilization laws based on California's model before progressing to murder of the disabled and eventually the Holocaust. Unlike historical eugenics, modern genetic selection isn't state-controlled or coercive, but instead driven by individual health choices. The question becomes not whether to allow embryo selection but how much modification is acceptable. Diversity isn't merely about redressing historical wrongs or institutional benefits-it's humanity's fundamental survival strategy. Random mutation, a pillar of Darwinian evolution, creates the diversity that allowed our species to adapt and thrive through changing conditions. Today's parents, if given genetic choice, would likely select for traits currently valued-intelligence, height, appearance-reflecting cultural biases of our time. Throughout history, technological advantages have created power divides between populations. Genetic technologies risk creating unbridgeable genetic gaps if only available to the wealthy, though many technologies begin with elite adoption before becoming widely accessible. Governments may be incentivized to make genetic engineering broadly available to reduce healthcare costs.

第10章

Our Genetic Future

The genetic revolution represents one of humanity's greatest opportunities for advancing health and wellbeing. We will inevitably demand access to these technologies for ourselves and our children as we continue our perpetual struggle against nature's cruelty and pursue our aspirations to transcend biological limitations. Any effective international regime would need to both enable responsible science and enforce limited restrictions, striking an impossible-seeming balance. Draw regulations too permissively and opponents revolt; too restrictively and people seek underground alternatives; too vaguely and they become meaningless. Without global standards, we risk an international genetic arms race. Creating an international framework for genetic engineering requires threading an impossibly narrow needle. It must respect constituencies uncomfortable with germline engineering while not impeding scientific progress worth trillions in commerce and human wellbeing. Realistically, only the most obvious violations of human dignity could be universally prohibited: dangerous human experimentation, excessive human-animal gene mixing, and engineering synthetic traits that fundamentally challenge human identity. Given these immense challenges, our immediate priority must be public education and engagement. Every nation should develop its own bioethics commission and regulatory framework reflecting its values, following exemplary models like the UK's Human Fertilisation and Embryology Authority. But we can't wait for governments to act-each of us must educate ourselves and others before it's too late. This global dialogue could begin with an international commission of scientists, thinkers, and religious leaders developing key questions about genetic technologies: ensuring broad access, setting appropriate limits, determining information rights, establishing embryo selection policies, addressing germline editing, preventing abuses, and creating inclusive decision-making processes. Deploying genetic technologies wisely will require drawing on our best humanist values and strengthening our commitment to diversity, equality, and our common humanity. While the technologies are new, the philosophical frameworks needed to use them responsibly are often ancient. The process of developing international norms and regulations will be arduous and may seem impossible. Yet simply attempting this global conversation brings more people into determining humanity's future. We cannot stop genetic enhancement of our species, but we can influence how this transformation unfolds.

★★★★★

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』を最後まで読み終えました

100万人以上の学習者に愛用されています

“23日間、毎日使い続けています。今では日課の一部です。”

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『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』の主要テーマ

human genetic engineering
embryo selection ethics
directed evolution
crispr technology impact
future of reproduction

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』の名言

We are beginning to hack Darwin.
Our mutations will no longer be random but self-designed.
Conception through sex may be seen as unnecessarily risky.
Every human needs to participate in answering these questions.
Darwin's rules are changing.

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』の登場人物

Jamie MetzlAuthor and expert on the genetic revolution
Samuel SchenkScientist who discovered egg fertilization in 1878
Louise BrownThe first person born via IVF (test-tube baby)
Charles DarwinNaturalist whose rules of evolution are changing

著者について

『Hacking Darwin: Genetic Engineering and the Future of Humanity（ハッキング・ダーウィン：遺伝子工学と人類の未来）』の著者であるジェイミー・メッツルは、新興科学がもたらす倫理的・社会的影響を解読することで知られる、ベストセラー作家、テクノロジー・フューチャリスト、そして地政学の専門家です。

アトランティック・カウンシルのシニア・フェローであり、元国家安全保障会議（NSC）職員でもあるメッツルの活動は、バイオテクノロジー、AI、そしてグローバル・ガバナンスを橋渡ししています。『Hacking Darwin』における遺伝子工学のノンフィクション的探求は、世界保健機関（WHO）のヒトゲノム編集に関する専門家諮問委員会の委員としての役割や、数十年にわたる政策指導者としての経験に基づいています。

メッツルの高く評価されているSF小説『Genesis Code』や『Eternal Sonata』も同様にバイオテクノロジーの倫理問題に取り組んでおり、思索的な物語と現実世界の科学を融合させています。CNN、BBC、『60 Minutes』のコメンテーターとしても頻繁に活動しており、オックスフォード大学で東南アジア史の博士号を、ハーバード大学で法務博士号を取得しています。

『Hacking Darwin』は15言語に翻訳され、バイオテクノロジーの安全保障に関する議会公聴会でも引用されています。アイアンマン・トライアスリートでもあるメッツルの学際的な権威は、学術界、政策、そして公共の議論にまで及んでいます。

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"Reading used to feel like a chore. Now it’s just part of my lifestyle."

@Erin, Investment Banking Associate , NYC

254

"Feels effortless compared to reading. I’ve finished 6 books this month already."

@djmikemoore

"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

@Pitiful

4.5K

"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."

@SofiaP

"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"

@Jaded_Falcon

201

"It is great for me to learn something from the book without reading it."

@OojasSalunke

"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."

@Leo, Law Student, UPenn

483

"Makes me feel smarter every time before going to work"

@Cashflowbubu

BeFreedがウェブ上でどのように話題になっているかをもっと見る

コロンビア大学卒業生がサンフランシスコで開発

LOVED BY

1,000,000+ curious minds.

4.7

avg rating

1M+ learners

"Instead of endless scrolling, I just hit play on BeFreed. It saves me so much time."

@Moemenn

"I never knew where to start with nonfiction—BeFreed’s book lists turned into podcasts gave me a clear path."

@Chloe, Solo founder, LA

117

"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."

@Raaaaaachelw

"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."

@Matt, YC alum

108

"Reading used to feel like a chore. Now it’s just part of my lifestyle."

@Erin, Investment Banking Associate , NYC

254

"Feels effortless compared to reading. I’ve finished 6 books this month already."

@djmikemoore

"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

@Pitiful

4.5K

"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."

@SofiaP

"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"

@Jaded_Falcon

201

"It is great for me to learn something from the book without reading it."

@OojasSalunke

"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."

@Leo, Law Student, UPenn

483

"Makes me feel smarter every time before going to work"

@Cashflowbubu

"Instead of endless scrolling, I just hit play on BeFreed. It saves me so much time."

@Moemenn

"I never knew where to start with nonfiction—BeFreed’s book lists turned into podcasts gave me a clear path."

@Chloe, Solo founder, LA

117

"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."

@Raaaaaachelw

"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."

@Matt, YC alum

108

"Reading used to feel like a chore. Now it’s just part of my lifestyle."

@Erin, Investment Banking Associate , NYC

254

"Feels effortless compared to reading. I’ve finished 6 books this month already."

@djmikemoore

"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

@Pitiful

4.5K

"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."

@SofiaP

"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"

@Jaded_Falcon

201

"It is great for me to learn something from the book without reading it."

@OojasSalunke

"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."

@Leo, Law Student, UPenn

483

"Makes me feel smarter every time before going to work"

@Cashflowbubu

"Instead of endless scrolling, I just hit play on BeFreed. It saves me so much time."

@Moemenn

"I never knew where to start with nonfiction—BeFreed’s book lists turned into podcasts gave me a clear path."

@Chloe, Solo founder, LA

117

"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."

@Raaaaaachelw

"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."

@Matt, YC alum

108

"Reading used to feel like a chore. Now it’s just part of my lifestyle."

@Erin, Investment Banking Associate , NYC

254

"Feels effortless compared to reading. I’ve finished 6 books this month already."

@djmikemoore

"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."

@Pitiful

4.5K

"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."

@SofiaP

"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"

@Jaded_Falcon

201

"It is great for me to learn something from the book without reading it."

@OojasSalunke

"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."

@Leo, Law Student, UPenn

483

"Makes me feel smarter every time before going to work"

@Cashflowbubu

BeFreedがウェブ上でどのように話題になっているかをもっと見る

今すぐ学習の旅を始めよう

第5章

ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める

概要『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』の概要

1冊の本。さまざまな聴き方。

The Genetic Revolution Is Here, Whether We're Ready Or Not

Darwin's Rules Are Changing

聴きながら、すべての言葉を目で追えます

Reading Our Genetic Code

The Future of Human Reproduction

『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

Decoding Complex Human Traits

Understanding Nature vs. Nurture

聴きながら、すべての言葉を目で追えます

The CRISPR Revolution

The Quest for Immortality

『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

Ethical Challenges of the Genetic Revolution

Our Genetic Future

『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』を最後まで読み終えました

『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』の主要テーマ

『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』の名言

『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』の登場人物

著者について

ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決めるの要約をダウンロード

他のユーザーのお気に入り

この本に関するよくある質問

What is Hacking Darwin by Jamie Metzl about?

Who should read Hacking Darwin?

Is Hacking Darwin worth reading in 2025?

What are the main ethical concerns in Hacking Darwin?

もっと見る

1,000,000+ curious minds.

1,000,000+ curious minds.

1冊の本。さまざまな聴き方。

The Genetic Revolution Is Here, Whether We're Ready Or Not

Darwin's Rules Are Changing

聴きながら、すべての言葉を目で追えます

Reading Our Genetic Code

The Future of Human Reproduction

『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

Decoding Complex Human Traits

Understanding Nature vs. Nurture

聴きながら、すべての言葉を目で追えます

The CRISPR Revolution

The Quest for Immortality

『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

Ethical Challenges of the Genetic Revolution

Our Genetic Future

『ハッキング・ダーウィン 「遺伝子操作」が人類の未来を決める』を最後まで読み終えました

他のユーザーのお気に入り

もっと見る

ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』の概要

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』を最後まで読み終えました

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』の主要テーマ

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』の名言

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』の登場人物

ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決めるの要約をダウンロード

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』をもっと深く楽しむ

『ハッキング・ダーウィン　「遺伝子操作」が人類の未来を決める』を最後まで読み終えました