
Nobel laureate Elizabeth Blackburn reveals how your daily habits affect telomeres - the biological clocks determining aging. Jon Kabat-Zinn calls it "one of the most exciting health books in decades," showing how mindfulness and lifestyle choices can literally extend your lifespan.
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Right now, as you read these words, billions of your cells are dividing, renewing, dying. With each division, something remarkable happens: protective caps at the ends of your chromosomes-called telomeres-grow slightly shorter. Think of them as the plastic tips on shoelaces, preventing your genetic material from fraying. This microscopic process marks time more accurately than any birthday candle or wrinkle ever could. When Elizabeth Blackburn won the Nobel Prize in 2009 for discovering these structures, she revealed something revolutionary: we don't all age at the same rate, and our daily choices dramatically influence our cellular clock. Consider two fifty-year-olds: Kara appears exhausted, catches every cold, shows early heart disease. Lisa radiates energy despite facing similar life challenges. What separates them? Their telomeres tell different stories. At birth, our telomeres measure about 10,000 base pairs. By sixty-five, they've shrunk to roughly 4,800. When they become critically short, cells stop dividing-they become senescent, like rotten apples contaminating the healthy ones around them. These zombie cells can't renew themselves, their energy factories malfunction, and they release inflammatory substances that damage surrounding tissue. The consequences appear everywhere: skin develops wrinkles as collagen-producing cells age prematurely, bones weaken, hair grays when pigment-producing stem cells can't replenish themselves. Most critically, your immune system falters. T-cells that once fought viruses and cancer become ineffective, releasing inflammatory molecules that create what scientists call "inflamm-aging"-chronic inflammation contributing to diabetes, heart disease, autoimmune disorders, and dementia. This is your "diseasespan," years marked by chronic illness rather than vibrant health. You have far more control over how you age than you ever imagined.
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Creato da alumni della Columbia University a San Francisco

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