
Dive into the CRISPR revolution with Isaacson's portrait of Nobel Prize-winner Jennifer Doudna, whose gene-editing breakthrough could rewrite humanity's future. When Oprah praised this "page-turning detective story," the scientific thriller that even Atul Gawande calls "mind-blowing" became unmissable.
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A biochemist stares at the ceiling in Berkeley, her mind racing. The coronavirus is spreading. Her lab is shutting down. But Jennifer Doudna knows something most people don't: the gene-editing tool she helped pioneer-CRISPR-was born from bacteria's ancient war against viruses. If any technology could help humanity fight back, this was it. Within days, she mobilizes teams across campus, transforming research spaces into testing facilities, rushing to deploy a tool that would earn her a Nobel Prize later that year. But beneath the urgency lies a question that keeps her awake: Should we use this technology not just to fight viruses today, but to redesign humans to resist them forever? We've entered the third great revolution of modern times. After physics gave us the atomic age and computers gave us the digital age, we now face the life-science revolution-where children will study genetic code alongside computer code, and the very definition of being human hangs in the balance. Growing up blonde and blue-eyed in predominantly Polynesian Hawaii, Doudna knew what it felt like not to belong. Classmates called her "haole"-outsider. She felt like a freak. But alienation has a strange way of forging scientists. That discomfort sparked a curiosity about how humans fit into the natural world, a question that would shape her entire career. When her father handed her a worn paperback of "The Double Helix," she thought she was getting a detective story. She was right-just not the kind she expected. James Watson's account of discovering DNA's structure revealed that women could be scientists, that molecules' shapes determined their functions, and that science itself was detective work. When her high school guidance counselor told her "girls don't do science," the words didn't crush her-they crystallized her resolve.
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Cree par des anciens de Columbia University a San Francisco
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Cree par des anciens de Columbia University a San Francisco

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